• Cephalexin 500mg PO q6h
DOI: 10
Cephalosporins are the largest group of beta-lactam antibiotics, cover a broad range of organisms, are generally well-tolerated, are easy to administer, and are
, H
Food and Drug Administration (FDA) in 1970 and is classified as a first-generation
aureus, E
In children with minor skin infections (e
Adults and patients at least
, psoriasis)
Cephamycins are drugs that were originally produced by Streptomyces but are now synthetic
In the treatment of β-hemolytic streptococcal infections, duration of at least 10 days is recommended
The usual dose is 250 mg every 6 hours, but a dose of 500 mg every 12 hours may be administered ( 2
When doing empiric abx coverage, you want to think of covering the following as needed
In such cases, directed therapy should be administered as described Principles of antimicrobial therapy of Pseudomonas aeruginosa infections; Pseudomonas aeruginosa infections of the eye, ear, urinary tract, gastrointestinal tract, and central nervous system; Recurrent simple cystitis in women; Renal and perinephric abscess; Sampling and evaluation of voided urine in the diagnosis of urinary tract infection in In children with minor skin infections (e
In 20 patients ciprofloxacin was given alone and in 10 patients (including 8 compromised hosts) in combination with an aminoglycoside (9) or azlocillin (1)
[1] Cellulitis typically presents as a poorly demarcated, warm, erythematous area with associated edema and
This guidance document provides recommendations to clinicians for treatment of infections caused by extended-spectrum β-lactamase producing Enterobacterales (ESBL-E), carbapenem-resistant Enterobacterales (CRE), and difficult-to-treat Pseudomonas aeruginosa (DTR-P
aeruginosa in Egypt
The general principles of antimicrobial treatment of infections caused by P
In severely ill, or risk for MRSA, empiric coverage traditionally with vancomycin IV, although daptomycin, ceftaroline or linezolid among others would potentially service depending on the clinical presentation
Alternative dosing:1000 mg po three times a day; Ciprofloxacin 750 mg PO twice daily
16 Cephalexin usually requires dosing four times daily but offers a • Not polymicrobial or bacteremic with Pseudomonas • Not neutropenic, HCST/SOT, HIV with CD4 <200 • Remains hemodynamically stable at day 7 • Been afebrile ≥48 hours (at day 7) Comments • Ciprofloxacin use is not preferred unless necessary due to allergy or need for Pseudomonas coverage due to increasing resistance amongst E